Medical Article review Essay Example | Topics and Well Written Essays - 1750 words

Medical Article review - Essay Example cs and different types of benign tumours exhibit numerous morphological features that mislead and confuse pathologists who are making efforts by identifying the invasive endocervical adenocarcinoma. The authors of this article seek to present a detailed analysis of how to distinguish the endocervical adenocarcinoma from the malignant mimics and benign tumours. Being able to differentiate the cancerous adenocarcinoma in situ from the benign tumours is a critical move towards positive diagnosis of the different types of cervical cancer that women suffer. The authors define adenocarcinoma in situ in the first section of the article. This is denoted as a pre-cursor of the invasive cervical adenocarcinoma. According to the authors, there is evidence linking adenocarcinoma in situ and the human papilloma virus (HPV), specifically the HPV type 18. Usually, many patients diagnosed with adenocarcinoma in situ present no visible symptoms and the lesions are only detectable after a specific tes ting and evaluation. In some cases, though, virginal bleeding may serve as a symptom of the presence of the cancerous lesions (Loureiro & Oliva, 2014). The article describes the architectural and cytologic features used in the diagnosis of adenocarcinoma in situ. Usually, adenocarcinoma exhibits partial or complete involvement of glands in the endocervix. Moreover, adenocarcinoma may exhibit the preservation of normal glandular architecture and may often change to look like normal endocervical epithelium. On the other hand, cytologic features considered during diagnosis include the presence of musin in the cytoplasm as well as the level of stratification, crowding, enlargement or the presence of hyperchromatic nuclei. Other cytologic features that identify adenocarcinoma in situ include frequent mitoses and either small or inconspicuous nucleoli. Sometimes, multiple nuclei, which are smaller, may be present. In a bid to enlighten the reader further, the article discusses where